TEST CODE: 008823

SCREENING FOR: HEALTHY ADULTS

Learn if you are more likely to develop certain conditions so you can take steps to stay healthy.

TURNAROUND TIME: 10–21 calendar days (14 days on average)

PREFERRED SPECIMEN: 3mL whole blood in a purple-top tube

ALTERNATE SPECIMENS: DNA or saliva/assisted saliva

Genomed Genetic Cancer Screening

Early action saves lives. Understand your cancer risk.

The genetics of Cancer

About half of all men and one-third of all women in the US will develop cancer during their lifetimes. Approximately 5% to 10% of all cancers are hereditary. An additional 10% to 30% have a close family member who also had cancer, suggesting a familial link even though no specific hereditary link was found. And 60% to 85% of cancer patients have what's called sporadic cancer, meaning the cancer does not seem connected to inherited genetic traits, or is the result of many different factors. In hereditary cancer, an increased risk of developing certain cancers is passed down through families via their genes. The past few decades have seen incredible advances in genetic knowledge, and we have now identified many genes associated with cancer. If you have an alteration in one of these genes, your risk of developing certain types of cancer is significantly higher than that of the general population.

Who should consider Cancer genetics testing?

Genetic testing may be appropriate if:

– You or a relative have had a rare cancer (e.g., ovarian, pancreatic, male breast, metastatic prostate, triple negative breast, medullary thyroid)

– You or a relative have had an early onset cancer (e.g., colorectal, endometrial (uterine), or breast cancer diagnosed prior to age 50)

– You or a relative have been diagnosed with two different cancers; this might be cancer in two different areas of the body (e.g., a colon and a uterine cancer) or two separate cancers in the same organ (e.g., bilateral breast cancer)

– There are multiple relatives on the same side of your family with the same or associated types of cancer (e.g., breast/ovarian/pancreatic/prostate or colorectal/endometrial [uterine]/gastric [stomach]/ovarian/pancreatic)

– You have had 10 or more colorectal polyps found during your colonoscopies

– You have Ashkenazi Jewish ancestry on either side of your family

– You have a relative who tested positive for a genetic variant related to cancer risk

*Relatives to consider include siblings, children, parents, aunts, uncles, and grandparents.

What are the genes tested?

We Looks at 61 genes to assess your risk of developing an inherited form of cancers such as:

– Breast cancer

– Colorectal cancer

– Cutaneous melanoma

– Gastric cancer

– Ovarian cancer

– Pancreatic cancer

– Prostate cancer

– Renal cell cancer

– Thyroid cancer

– Uterine cancer

* Please contact us for the complete list of genes included on the multi-cancer panel and associated cancers by system.

What can genetic testing tell me?

A POSITIVE TEST RESULT CAN:

• Pinpoint your risk of developing cancer, enabling you to make informed medical decisions to reduce risk • Provide an explanation for your personal or family history of cancer
• Identify other at-risk relatives for whom genetic testing is recommended

A NEGATIVE TEST RESULT:

• Means that you do not have an alteration in the genes tested
• Your overall cancer risk depends on your medical history, family history, and environment

AN UNCERTAIN VARIANT TEST RESULT:

• Means that an alteration was identified, but it is not currently known if that alteration increases risk
• Should not be used to guide your medical care

Take action based on your results.

With Genomed, you can make health decisions based on your results. Our medical-grade tests are the same tests used by doctors and genetic counselors. Based on your results, you can work with your healthcare provider to consider:

– increased or earlier screenings

– lifestyle modifications

– early intervention to prevent the onset of disease